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Dr Jenny MacLennan

Research Associate
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Biography

I trained in medicine at Cambridge and Oxford, and worked as a clinician in medicine, paediatrics, and general practice in the UK and Africa before more formal research training with an MSc in Epidemiology at the London School of Hygiene and Tropical Medicine.  I have undertaken research in the National Perinatal Epidemiology Unit, Oxford, the Oxford Vaccine Group, Oxford, the Kenya Medical Research Unit, Kilifi, Kenya, the Medical Research Council Unit, The Gambia, the Malawi-Liverpool-Wellcome Trust Research Programme, Blantyre, Malawi and two periods of time working with Professor Martin Maiden in the Department of Zoology, Oxford. I am affiliated to the group as a Research Associate. 

The main focus of my research has been in vaccination against meningococcal disease, immunological memory, risk factors for carriage and transmission of Neisseria meningitidis, and the effects of vaccination on carriage.  I am also interested in the role of non pathogenic Neisseria species in the development of natural immunity against Neisseria meningitidis.  Other research interests include understanding transmission and immunity against Non-typhoidal salmonella. 

Publications

Maiden MC, MacLennan JM. Editorial commentary: fifteen years of protection by meningococcal C conjugate vaccines: lessons from disease surveillance.  Clin Infect Dis. 2014 Nov 1;59(9):1222-4 

Ibarz-Pavón AB, MacLennan J, Andrews NJ, Gray SJ, Urwin R, Clarke SC, Walker AM, Evans MR, Kroll JS, Neal KR, Ala'aldeen D, Crook DW, Cann K, Harrison S, Cunningham R, Baxter D, Kaczmarski E, McCarthy ND, Jolley KA, Cameron JC, Stuart JM, Maiden MC. Changes in serogroup and genotype prevalence among carried meningococci in the United Kingdom during vaccine implementation. Journal of Infectious Diseases. 2011 Oct 1;204(7):1046-53 

J MacLennan, G Kafatos, K Neal, N Andrews, JC Cameron, R Roberts, MR Evans, K Cann, DN Baxter, MCJ Maiden, and JS Stuart on behalf of the UK meningococcal carriage group.  Social behaviour and meningococcal carriage in British teenagers. Emerging Infectious Diseases 2006 Jun;12(6):950-7 

J MacLennan, S Obaro, J Deeks, D Lake, C Elie, G Carlone, ER Moxon, and B Greenwood. Immunologic memory 5 years after meningococcal A/C conjugate vaccination in infancy. Journal of Infectious Diseases 2001;183:97-104.